The Portuguese received a lot of stick from the home supporters throughout the last-16 tie due to thefact he represented their bitter rivals Real Madrid for nine years.
Ronaldo was also on the end of some rough tackles from the Atletico players, who looked to stamp their authority on the game at the Wanda Metropolitano Stadium.
During one moment on Wednesday night there was a break in play and the fans turned on the former Real Madrid star, chanting a number of things in his direction.
Ronaldo had been ignoring the stickup until this moment but decided torespond with a hand gesture that was picked up by fans on social media.
Holding one hand up towards the crowd Ronaldo spread his fingers apart to make the number five – the amount of times he has won the Champions League.